[Sar1, Ile8]-Angiotensin II
添加购物车名称 | [Sar1, Ile8]-Angiotensin II |
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CAS No. | 67724-27-0 |
目录号 | ONP10022 |
规格 | mg/g |
纯度 | ≥98% |
价格 | 更多在线询价 |
贮存 | -20°C |
分子量 | 968.15 |
序列结构 | H-SAR-ARG-VAL-TYR-ILE-HIS-PRO-ILE-OH |
库存 | |
产品简述 | The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the most potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1, Ile8] derivative of angiotensin II. However, this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells, and never reduced aldosterone production to basal levels. |